Global dynamics for an age-structured HIV virus infection model with cellular infection and antiretroviral therapy

作者：

Highlights：

• An age-structured virus infection model with cell-to-cell infection is investigated.

• The threshold dynamics of the model is studied.

• Blocking cell-to-cell infection can effectively suppress virus infection.

摘要

•An age-structured virus infection model with cell-to-cell infection is investigated.•The threshold dynamics of the model is studied.•Blocking cell-to-cell infection can effectively suppress virus infection.

论文关键词：Age-structure,Cell-to-cell infection,The basic reproduction number,Lyapunov functionals,Globally asymptotically stable

论文评审过程：Received 19 July 2016, Revised 9 November 2016, Accepted 30 January 2017, Available online 11 March 2017, Version of Record 11 March 2017.

论文官网地址：https://doi.org/10.1016/j.amc.2017.01.064