A stochastic model of bacterial infection associated with neutrophils

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摘要

We study stochastic phenomena for a model of bacterial infection and neutrophils defense. Sufficient conditions of stochastic permanence and extinction for the random model are discussed. To explore the effect of different noises on the bacteria dynamics, we estimate the confidence intervals by the Stochastic Sensitivity Function (SSF) technique. Numerical simulations show the dramatic change of bacterial concentration induced by noises, that is, the solution with initial value near the positive deterministic equilibrium can shift into the extinct zone due to the effect of noises.

论文关键词:Stochastic system,Bacterial dynamics,Survival analysis,Bacterial infection,Noise-induced extinction

论文评审过程:Received 7 February 2019, Revised 13 September 2019, Accepted 23 December 2019, Available online 13 January 2020, Version of Record 13 January 2020.

论文官网地址:https://doi.org/10.1016/j.amc.2019.125025