Complex dynamics of a tumor-immune system with antigenicity

作者:

Highlights:

• A conceptual model on tumor-immune interaction is proposed.

• The model has complicated dynamical behavior.

• Numerical simulations reveal some clinical phenomena.

• Biological implications of the findings are provided.

摘要

•A conceptual model on tumor-immune interaction is proposed.•The model has complicated dynamical behavior.•Numerical simulations reveal some clinical phenomena.•Biological implications of the findings are provided.

论文关键词:Tumor-immune interaction,Antigenicity,Stability,Hopf bifurcation,Bogdanov–Takens bifurcation

论文评审过程:Received 19 September 2020, Revised 1 December 2020, Accepted 26 January 2021, Available online 21 February 2021, Version of Record 21 February 2021.

论文官网地址:https://doi.org/10.1016/j.amc.2021.126052

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