Brain network topology unraveling epilepsy and ASD Association: Automated EEG-based diagnostic model

作者:

Highlights:

• Mathematical computation unraveled neural topology shared by ASD & Epilepsy.

• Proposed Visibility graph-based method show Hemisphere, Local & Global connectivity.

• Functional overlap exists among ASD + E and ASD (49%) as well as ASD + E and E (55%).

• EEG-based neural metrics support automated multiclassification with accuracy 98.2%.

• Brain topology variations with maturation brings disorder diversity & comorbidity.

摘要

•Mathematical computation unraveled neural topology shared by ASD & Epilepsy.•Proposed Visibility graph-based method show Hemisphere, Local & Global connectivity.•Functional overlap exists among ASD + E and ASD (49%) as well as ASD + E and E (55%).•EEG-based neural metrics support automated multiclassification with accuracy 98.2%.•Brain topology variations with maturation brings disorder diversity & comorbidity.

论文关键词:Association,Autism spectrum disorder,Co-morbidity,Electroencephalography,Epilepsy,Functional,Network metrics,Topology

论文评审过程:Received 11 May 2021, Revised 10 August 2021, Accepted 11 August 2021, Available online 18 August 2021, Version of Record 20 August 2021.

论文官网地址:https://doi.org/10.1016/j.eswa.2021.115762