A 1.375-approximation algorithm for unsigned translocation sorting

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摘要

Translocation has been long learned as a basic operation to rearrange the structure of a genome. Translocation sorting asks to find a shortest sequence of translocations that transforms one genome into another, which has attracted attention of many scientists in algorithm design. Signed translocation sorting can be solved in polynomial time. Unsigned translocation sorting turns out to be NP-Hard and Max-SNP-Hard. The best known approximation algorithm by now for unsigned translocation sorting can achieve a performance ratio 1.408. In this paper, we propose a new approximation algorithm for unsigned translocation sorting which can achieve a asymptotic performance ratio 1.375.

论文关键词:Genome rearrangement,Approximation algorithm,Translocation,Complexity

论文评审过程:Received 14 September 2017, Revised 26 April 2020, Accepted 5 May 2020, Available online 22 May 2020, Version of Record 1 June 2020.

论文官网地址:https://doi.org/10.1016/j.jcss.2020.05.004