Zero-crossing interval correction in tracing eye-fundus blood vessels

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We are developing a health screening system for color eye-fundus photography. The system is designed to detect the first signs of adult diseases, for which purpose it is important to detect and trace eye blood vessels. This paper describes a method of finding the papilla by Hough transform, and from there tracing blood vessels by a second-order derivative Gaussian filter. The width of the blood vessel is obtained as the zero-crossing interval of the filter output. The filter is adjustable to the current width of the blood vessel being traced. In this process, since the obtained zero-crossing interval is larger than the true width of an ideal step-wise blood vessel, it is corrected at each step.

论文关键词:Medical image processing,Fundus photography,Hough transform,Zero-crossing Gaussian filter,Blood vessel tracing

论文评审过程:Received 5 May 1987, Revised 28 September 1987, Available online 19 May 2003.

论文官网地址:https://doi.org/10.1016/0031-3203(88)90057-X