Integration of prior knowledge of measurement noise in kernel density classification

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Samples can be measured with different precisions and reliabilities in different experiments, or even within the same experiment. These varying levels of measurement noise may deteriorate the performance of a pattern recognition system, if not treated with care. Here we seek to investigate the benefit of incorporating prior knowledge about measurement noise into system construction. We propose a kernel density classifier which integrates such prior knowledge. Instead of using an identical kernel for each sample, we transform the prior knowledge into a distinct kernel for each sample. The integration procedure is straightforward and easy to interpret. In addition, we show how to estimate the diverse measurement noise levels in a real world dataset. Compared to the basic methods, the new kernel density classifier can give a significantly better classification performance. As expected, this improvement is more obvious for small sample size datasets and large number of features.

论文关键词:Prior knowledge,Measurement noise,Kernel method,Parzen,Protein complex,mRNA co-expression coefficient

论文评审过程:Received 27 October 2006, Revised 27 April 2007, Accepted 8 May 2007, Available online 24 May 2007.

论文官网地址:https://doi.org/10.1016/j.patcog.2007.05.005