Mathematical analysis of the dynamics of visceral leishmaniasis in the Sudan

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摘要

In this paper we develop a mathematical model to study the dynamics of visceral leishmaniasis in the Sudan. To develop this model we consider the dynamics of the disease between three different populations, human, reservoir and vector populations. The model is analyzed at equilibrium and the stability of the equilibria is analyzed. The basic reproduction number is derived, and the threshold conditions for disease elimination established. Results show that the disease can be eliminated under certain conditions. Simulations of the model show that human treatment helps in disease control, and its synergy with vector control will more likely result in the elimination of the disease.

论文关键词:Visceral leishmaniasis,PKDL,Animal reservoir,Sandfly,Basic reproduction number

论文评审过程:Available online 30 July 2010.

论文官网地址:https://doi.org/10.1016/j.amc.2010.07.069