Hopf bifurcation analysis of delayed model of thymic infection with HIV-1

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摘要

In this paper, a delayed differential equation model that describes infection of thymus with HIV-1 is considered. We first investigate the existence and stability of the equilibria and then we study the effect of the time delay on the stability of the infected equilibrium. Criteria are given to ensure that the infected equilibrium is asymptotically stable for all delay. Finally, by using a delay as a bifurcation parameter, the existence of Hopf bifurcation is investigated. Numerical simulations are presented to illustrate the analytical results.

论文关键词:HIV-1,Thymus model,Delay,Stability,Hopf bifurcation

论文评审过程:Available online 16 June 2012.

论文官网地址:https://doi.org/10.1016/j.amc.2012.05.038