Signal power amplification of intracellular calcium dynamics with non-Gaussian noises and time delay

摘要

The effect of non-Gaussian noises on stochastic resonance of intracellular Ca2+ concentration in intracellular calcium oscillation(ICO) system with time delay is investigated by means of second-order stochastic Runge–Kutta type algorithm. By simulating the signal power amplification(SPA), the results indicate: there are respectively continuous values and a value of the parameter p(which is used to control the degree of the departure from the non-Gaussian noise and Gaussian noise.) to enhance reverse resonance in the behavior of SPA vs. p in cytosol and calcium store, namely continuous reverse resonance occurs in cytosol and reverse resonance occurs in calcium store. Moreover, SPA monotonically decreases as non-Gaussian noises strengthen, and SPA fast decays to constant as correlation time of non-Gaussian noises increases.