Pharmacokinetic model based on multifactor uncertain differential equation

作者：

Highlights：

• Give a pharmacokinetic model based on multifactor uncertain differential equations.

• Several essential pharmacokinetic indexes are studied.

• A paradox of the stochastic pharmacokinetic model is pointed out.

摘要

•Give a pharmacokinetic model based on multifactor uncertain differential equations.•Several essential pharmacokinetic indexes are studied.•A paradox of the stochastic pharmacokinetic model is pointed out.

论文关键词：Uncertain differential equations,Pharmacokinetics,Liu process,α-path,Uncertainty theory

论文评审过程：Received 2 May 2020, Revised 13 August 2020, Accepted 3 October 2020, Available online 20 October 2020, Version of Record 20 October 2020.

论文官网地址：https://doi.org/10.1016/j.amc.2020.125722