A decision-making mechanism for assessing risk factor significance in cardiovascular diseases

作者:

Highlights:

• Despite lots of diagnostic and treatment suggestions, CVDs continue to merit investigation due to their diverse risk factors.

• To assist doctors in identifying significance of CVD risk factors, I propose a novel ranking and attribute selection method.

• Seven kinds of classifiers are applied to generate attribute-ranked datasets to identify the ideal number of attributes.

• The results indicate that the proposed method is significantly better than whole factors and state-of-the-art algorithms.

• Since such knowledge can reduce treatment costs and thus lower the economic burden of healthcare.

摘要

Cardiovascular diseases (CVDs) are severe diseases whose growing incidence worldwide has spurred increased national healthcare spending. Despite numerous diagnostic and treatment suggestions, CVDs continue to merit investigation due to their diverse risk factors, some of which are positively, negatively, or not correlated. To assist doctors and researchers in identifying the significance of CVD risk factors, in this study we propose a novel ranking and attribute (or feature) selection algorithm. We applied seven popular machine learning technologies to generate attribute-ranked datasets in order to identify the ideal number of factors/attributes for each classifier. Above all, the results of the comparisons indicate that the performance of parts of factors after ranking and attribute selection was significantly better than the performance of whole factors and that of several state-of-the-art algorithms. Since such knowledge can aid the proper selection of factors of CVD patients and thereby assist doctors in making better decisions in diagnostics and treatment, our results can reduce treatment costs and thus lower the economic burden of healthcare.

论文关键词:Decision support systems,Medical decision making,Cardiovascular diseases,Feature ranking,Radial basis function network

论文评审过程:Received 12 March 2018, Revised 22 August 2018, Accepted 21 September 2018, Available online 28 September 2018, Version of Record 1 October 2018.

论文官网地址:https://doi.org/10.1016/j.dss.2018.09.004