Application of tabu search strategy for finding low energy structure of protein

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Objective:Understanding protein functionality would mean understanding the basics of life. This functionality follows a three-dimensional structure of proteins. Unfortunately till now it is not possible to obtain these structures artificially. This article offers a survey on the use of meta-heuristic methods in context of simplified models of protein folding.

论文关键词:Tabu search,Meta-heuristic,Hydrophobic–hydrophilic lattice model,Protein structure prediction

论文评审过程:Received 18 November 2004, Revised 24 January 2005, Accepted 22 February 2005, Available online 26 July 2005.

论文官网地址:https://doi.org/10.1016/j.artmed.2005.02.001