Statistical analysis of combined dose effects for experiments with two agents
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摘要
ObjectiveClassical isobologram analysis offers a way for analysing combined drug effects in dose–response experiments statistically. The aim is to determine as to whether two agents or drugs can be considered synergistic or antagonistic in their effect.
论文关键词：Combination index,Dose–response curves,Isobolograms,Logistic regression,MATLAB implementation
论文评审过程：Received 19 July 2004, Revised 17 January 2005, Accepted 20 January 2005, Available online 21 February 2006.
论文官网地址：https://doi.org/10.1016/j.artmed.2005.01.011
