Interactive web service system for exploration of biological pathways

作者:

Highlights:

• The study proposes a web service system for exploring pathways in an interactive manner.

• Pathways can be converted from a static format into an interactive format.

• The entries in one pathway can be moving or rotating, and multiple pathways can be displayed simultaneously without overlaps.

• The system can discovery all possible reaction paths between two selected genes and chosen reaction types.

• Automatic identification of common entries and similar reaction paths in two different pathways.

摘要

•The study proposes a web service system for exploring pathways in an interactive manner.•Pathways can be converted from a static format into an interactive format.•The entries in one pathway can be moving or rotating, and multiple pathways can be displayed simultaneously without overlaps.•The system can discovery all possible reaction paths between two selected genes and chosen reaction types.•Automatic identification of common entries and similar reaction paths in two different pathways.

论文关键词:Biological pathways,Medical information and modeling,Bioinformatics,Visualization,Data analysis

论文评审过程:Received 30 November 2013, Revised 19 May 2014, Accepted 12 July 2014, Available online 18 July 2014.

论文官网地址:https://doi.org/10.1016/j.artmed.2014.07.002