Analysis of cancer-related lncRNAs using gene ontology and KEGG pathways

作者：

Highlights：

• We investigated cancer-related lncRNAs using GO and KEGG enrichment scores of the co-expressed neighbors of lncRNAs.

• The biological analysis confirmed the crucial cancer associated GO term and KEGG pathways we screened out.

• This study provided novel insight of how lncRNAs may affect tumorigenesis.

摘要

•We investigated cancer-related lncRNAs using GO and KEGG enrichment scores of the co-expressed neighbors of lncRNAs.•The biological analysis confirmed the crucial cancer associated GO term and KEGG pathways we screened out.•This study provided novel insight of how lncRNAs may affect tumorigenesis.

论文关键词：Cancer-related lncRNA,Gene ontology,KEGG pathway,Minimum redundancy maximum relevance,Incremental feature selection,Dagging

论文评审过程：Received 12 December 2016, Revised 31 January 2017, Accepted 5 February 2017, Available online 13 February 2017, Version of Record 20 February 2017.

论文官网地址：https://doi.org/10.1016/j.artmed.2017.02.001