Computational normalization of H&E-stained histological images: Progress, challenges and future potential

作者:

Highlights:

• We present a review of normalization methods of H&E-stained histological images.

• Possible color variation sources of histological images are described.

• This paper describes used techniques from the correlated literature.

• The evaluation methods used by the correlated works are also presented.

• It discusses limitations of published works and indicates possible future research.

摘要

•We present a review of normalization methods of H&E-stained histological images.•Possible color variation sources of histological images are described.•This paper describes used techniques from the correlated literature.•The evaluation methods used by the correlated works are also presented.•It discusses limitations of published works and indicates possible future research.

论文关键词:Histological image analysis,Hematoxylin–eosin,Normalization,Color corrections

论文评审过程:Received 17 July 2018, Revised 13 September 2018, Accepted 20 October 2018, Available online 9 November 2018, Version of Record 20 March 2019.

论文官网地址:https://doi.org/10.1016/j.artmed.2018.10.004