Mixed-integer optimization approach to learning association rules for unplanned ICU transfer

作者:

Highlights:

• Early identifying unplanned transfer to intensive care unit from emergency department due to unexpected clinical deteriorations is formulated as a supervised learning problem.

• A new rule-based analytic method using optimization and data mining is developed.

• Significant association rules of key risk factors resulting in high-risk, unplanned transfers are formed.

• The developed method provides easy-to-interpret results beneficial for supporting clinical decisions.

摘要

•Early identifying unplanned transfer to intensive care unit from emergency department due to unexpected clinical deteriorations is formulated as a supervised learning problem.•A new rule-based analytic method using optimization and data mining is developed.•Significant association rules of key risk factors resulting in high-risk, unplanned transfers are formed.•The developed method provides easy-to-interpret results beneficial for supporting clinical decisions.

论文关键词:Emergency department,Critical care,Unplanned ICU transfer,Association rule,Mixed-integer optimization

论文评审过程:Received 20 March 2019, Revised 9 January 2020, Accepted 13 January 2020, Available online 30 January 2020, Version of Record 6 February 2020.

论文官网地址:https://doi.org/10.1016/j.artmed.2020.101806