Early temporal prediction of Type 2 Diabetes Risk Condition from a General Practitioner Electronic Health Record: A Multiple Instance Boosting Approach

作者:

Highlights:

• MIL-Boost is applied to predict insulin resistance worsening.

• MIL-Boost is applied to temporal EHR data stored by a general practitioner.

• MIL-Boost overcomes other competitors (Recall from 0.70 and up to 0.83).

• MIL-Boost identifies also non-conventional insulin resistance biomarkers.

• MIL-Boost may represent the main core of a clinical decision support system.

摘要

•MIL-Boost is applied to predict insulin resistance worsening.•MIL-Boost is applied to temporal EHR data stored by a general practitioner.•MIL-Boost overcomes other competitors (Recall from 0.70 and up to 0.83).•MIL-Boost identifies also non-conventional insulin resistance biomarkers.•MIL-Boost may represent the main core of a clinical decision support system.

论文关键词:Type 2 Diabetes,Machine Learning,Predictive Medicine,Temporal Analysis,Electronic Health Record,Clinical Decision Support System

论文评审过程:Received 29 July 2019, Revised 12 February 2020, Accepted 20 March 2020, Available online 6 May 2020, Version of Record 16 May 2020.

论文官网地址:https://doi.org/10.1016/j.artmed.2020.101847